| No | Hotel | Rooms | Score | |
|---|---|---|---|---|
| 1 |  |
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel | 177 | 8.80 |
| 2 | |
Hotel Cortez | 176 | 9.30 |
| 3 | |
Hotel Camino Real | 165 | 8.80 |
| 4 | |
Hotel Arenal | 87 | 7.00 |
| 5 | |
Hampton by Hilton Santa Cruz | 80 | 8.90 |
| 6 | |
LP Equipetrol | 72 | 8.10 |
| 7 | |
Hotel Plaza Center | 41 | 8.50 |
| 8 | |
Hotel LP Santa Cruz Centro | 39 | 8.30 |
| 9 | |
Buganvillas Hotel Suites | 38 | 7.60 |
| 10 | |
Torre Hotel Ejecutivo | 38 | 8.10 |
| 11 | |
Sun Hotel | 34 | 7.70 |
| 12 | |
La Siesta Hotel | 31 | 8.00 |
| 13 | |
Prince Hotel | 28 | 8.20 |
| 14 | |
Residencial IKANDIRE ll | 25 | 7.40 |
| 15 | |
Hotel Continental Park | 22 | 9.00 |
| 16 | |
Gran Hotel Canada | 19 | 6.20 |
| 17 | |
Hotel Sirari By Regina | 16 | 8.50 |
| 18 | |
Cosmopolitano Hotel Boutique | 9 | 9.10 |