| No | Hotel | Rooms | Score | |
|---|---|---|---|---|
| 1 |  |
Holiday Inn Express Hotel & Suites Mission-McAllen Area, an IHG Hotel | 76 | 9.10 |
| 2 | |
SureStay Hotel by Best Western Mission | 54 | 8.10 |
| 3 | |
Hampton Inn & Suites Mission | 15 | 8.70 |
| 4 | |
La Quinta by Wyndham Mission at West McAllen | 6 | 8.60 |